Topo IIIAlpha Polyclonal Antibody - BT-AP09128

Topo IIIAlpha Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP09128-20, BT-AP09128-50, BT-AP09128-100

Citations, Manuals and MSDS Available upon request.

Background: TOP3A(topoisomerase(DNA) III alpha) encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus reducing the number of supercoils and altering the topology of DNA. This enzyme forms a complex with BLM which functions in the regulation of recombination in somatic cells. Alternative splicing results in multiple transcript variants encoding different isoforms.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: TOP3A

Applications: WB, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Topo IIIalpha Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 112372

UniProt Accession: Human: Q13472; Mouse: O70157

Synonyms: TOP3A; TOP3; DNA topoisomerase 3-alpha; DNA topoisomerase III alpha

GeneID: Human: 7156; Mouse: 21975

Research Use Only