TOPRS Polyclonal Antibody - BT-AP15076

TOPRS Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP15076-20, BT-AP15076-50, BT-AP15076-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a nuclear protein which is serine and arginine rich, and contains a RING-type zinc finger domain. It is highly expressed in the testis, and functions as an ubiquitin-protein E3 ligase. Mutations in this gene are associated with retinitis pigmentosa type 31. Alternatively spliced transcript variants, encoding different isoforms, have been observed for this locus.

Research Areas: Epigenetics and nuclear signaling; Cancer

Target Protein: TOPORS

Applications: WB, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: E3 ubiquitin-protein ligase Topors

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q9NS56; Mouse: Q80Z37

Synonyms: E3 ubiquitin-protein ligase Topors;EC 6.3.2.-;SUMO1-protein E3 ligase Topors;Topoisomerase I-binding RING finger protein;Topoisomerase I-binding arginine/serine-rich protein;Tumor suppressor

GeneID: Human: 10210

Research Use Only