TORC3 Monoclonal Antibody - BT-MCA1217

TORC3 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA1217-50, BT-MCA1217-100

Citations, Manuals and MSDS Available upon request.

Background: This gene is a member of the CREB regulated transcription coactivator gene family. This family regulates CREB-dependent gene transcription in a phosphorylation-independent manner and may be selective for cAMP-responsive genes. The protein encoded by this gene may induce mitochondrial biogenesis and attenuate catecholamine signaling in adipose tissue. A translocation event between this gene and Notch coactivator mastermind-like gene 2, which results in a fusion protein, has been reported in mucoepidermoid carcinomas. Alternative splicing results in multiple transcript variants that encode different protein isoforms.

Research Areas: Epigenetics and nuclear signaling; Microbiology

Target Protein: CRTC3

Applications: WB, IHC-p, IF, ICC, ELISA

Reactivity: Human,Monkey

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: CREB-regulated transcription coactivator 3

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q6UUV7; Mouse: Q91X84

Synonyms: CRTC3; TORC3; CREB-regulated transcription coactivator 3; Transducer of regulated cAMP response element-binding protein 3; TORC-3; Transducer of CREB protein 3

GeneID: Human: 64784

Research Use Only