TPP1 Polyclonal Antibody - BT-AP15097

TPP1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP15097-20, BT-AP15097-50, BT-AP15097-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.

Research Areas: Neuroscience; Cell biology

Target Protein: TPP1

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Tripeptidyl-peptidase 1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: O14773; Mouse: O89023; Rat: Q9EQV6

Synonyms: Tripeptidyl-peptidase 1;TPP-1;EC 3.4.14.9;Cell growth-inhibiting gene 1 protein;Lysosomal pepstatin-insensitive protease;LPIC;Tripeptidyl aminopeptidase;Tripeptidyl-peptidase I;TPP-I

GeneID: Human: 1200

Research Use Only