TRADD Monoclonal Antibody - BT-MCA4457

TRADD Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4457-50, BT-MCA4457-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq, Jul 2008]

Research Areas: Cell Biology

Target Protein: TRADD

Applications: FCM

Clonality: Monoclonal

Clone ID: 3A1E8

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: TRADD

Immunogen: Purified recombinant fragment of human TRADD (AA: 1-177) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 34.2kDa

UniProt Accession: Q15628

Synonyms: Hs.89862

GeneID: 8717

Research Use Only