TRADD Polyclonal Antibody - BT-AP09166

TRADD Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP09166-20, BT-AP09166-50, BT-AP09166-100

Citations, Manuals and MSDS Available upon request.

Background: Tumor necrosis factor receptor type 1-associated DEATH domain protein encoded by TRADD is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. Tumor necrosis factor receptor type 1-associated DEATH domain protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway.

Research Areas: Cell Biology

Target Protein: TRADD

Applications: WB, IHC-p, ELISA

Reactivity: Human, Mouse, Monkey

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: TRADD Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 34247

UniProt Accession: Human: Q15628; Mouse: Q3U0V2

Synonyms: TRADD; Tumor necrosis factor receptor type 1-associated DEATH domain protein; TNFR1-associated DEATH domain protein; TNFRSF1A-associated via death domain

GeneID: Human: 8717; Mouse: 71609

Research Use Only