TRAF6BP/TAX1BP1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A17039-20, A17039-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Category: Polyclonal Antibodies
Applications: IHC-P, ELISA
Cross-reactivity: Human, Rat
Protein Weight: 91kDa
Observed Molecular Weight: Refer to figures
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 8887
SWISS: Q86VP1
Alternate Names: T6BP; TXBP151; CALCOCO3; TRAF6BP/TAX1BP1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: IHC-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, Cell Biology Developmental Biology, Apoptosis, Immunology Inflammation, NF-kB Signaling Pathway.
NCBI Alias: TAX1BP1
Research Use Only