Treacle Polyclonal Antibody - BT-AP09186

Treacle Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP09186-20, BT-AP09186-50, BT-AP09186-100

Citations, Manuals and MSDS Available upon request.

Background: TCOF1 (treacle ribosome biogenesis factor 1) encodes a nucleolar protein with a LIS1 homology domain. The protein is involved in ribosomal DNA gene transcription through its interaction with upstream binding factor (UBF). Mutations in TCOF1 have been associated with Treacher Collins syndrome, a disorder which includes abnormal craniofacial development. Multiple transcript variants encoding different isoforms have been found for TCOF1.

Research Areas: Signal Transduction

Target Protein: TCOF1

Applications: WB, IHC-p, IF, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Treacle Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 152104

UniProt Accession: Human: Q13428; Mouse: O08784

Synonyms: TCOF1; Treacle protein; Treacher Collins syndrome protein

GeneID: Human: 6949; Mouse: 21453

Research Use Only