TRI63 Polyclonal Antibody - BT-AP15141

TRI63 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP15141-20, BT-AP15141-50, BT-AP15141-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is an E3 ubiquitin ligase that localizes to the Z-line and M-line lattices of myofibrils. This protein plays an important role in the atrophy of skeletal and cardiac muscle and is required for the degradation of myosin heavy chain proteins, myosin light chain, myosin binding protein, and for muscle-type creatine kinase.

Research Areas: Metabolism

Target Protein: TRIM63

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: E3 ubiquitin-protein ligase TRIM63

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q969Q1; Mouse: Q38HM4; Rat: Q91Z63

Synonyms: E3 ubiquitin-protein ligase TRIM63;EC 6.3.2.-;Iris RING finger protein;Muscle-specific RING finger protein 1;MuRF-1;MuRF1;RING finger protein 28;Striated muscle RING zinc finger protein

GeneID: Human: 84676

Research Use Only