TRIF Polyclonal Antibody - BT-AP09200

TRIF Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP09200-20, BT-AP09200-50, BT-AP09200-100

Citations, Manuals and MSDS Available upon request.

Background: TICAM1 (toll like receptor adaptor molecule 1) encodes an adaptor protein containing a Toll/interleukin-1 receptor(TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the Toll-like receptors(TLRs) and signal-transduction components. This protein is involved in native immunity against invading pathogens. It specifically interacts with toll-like receptor 3, but not with other TLRs, and this association mediates dsRNA induction of interferon-beta through activation of nuclear factor kappa-B, during an antiviral immune response.

Research Areas: Immunology

Target Protein: TICAM-1

Applications: WB, ELISA

Reactivity: Human

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: TRIF Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 76422

UniProt Accession: Human: Q8IUC6; Mouse: Q80UF7

Synonyms: TIR domain-containing adapter molecule 1 (TICAM-1) (Proline-rich, vinculin and TIR domain-containing protein B) (Putative NF-kappa-B-activating protein 502H) (Toll-interleukin-1 receptor domain-contai

GeneID: Human: 148022; Mouse: 106759

Research Use Only