Product Description

TRIM24 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-63433-60, E-AB-63433-120, E-AB-63433-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: TRIM24

Target Synonym: TRIM24; PTC6; RNF82; TF1A; TIF1; TIF1A; TIF1ALPHA; hTIF1

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Signal transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: O15164

Background: The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human TRIM24 (NP_056989.2).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:1000-1:2000

Calculated MW: 113kDa/116kDa

Observed MW: 117kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only