TRIM5 Polyclonal Antibody - E-AB-65386

TRIM5 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-65386-60, E-AB-65386-120, E-AB-65386-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: TRIM5

Target Synonym: TRIM5; RNF88; TRIM5alpha

Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Immunology

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q9C035

Background: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coilel-coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Concentration: 1mg/mL

Immunogen: A synthetic peptide of human TRIM5 (NP_149083.2).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 29kDa/31kDa/37kDa/40kDa/46kDa/56kDa

Observed MW: 50kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only