Product Description

TRIPC Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA35544-50, RA35544-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: function:Component of PA700, an ATP-dependent multisubunit protein that activates the proteolytic activities of the multifunctional proteinase (20S proteasome) of the 26S complex. Specifically interacts with the ligand binding domain of the thyroid hormone receptor (in a thyroid hormone T3-independent manner) and with retinoid X receptor (RXR). Could be E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates., miscellaneous:A cysteine residue is required for ubiquitin-thioester formation., pathway:Protein modification; protein ubiquitination., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the UPL family. K-HECT subfamily., similarity:Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain., similarity:Contains 1 WWE domain., subunit:PA700 is composed of at least 16 distinct peptides ranging from 20-112 kDa.,

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 219

Protein Molecular Weight (kDa): 219

Storage: -20°C/1 year

Human Gene ID: 9320

Human SwissProt Number: Q14669

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only