Product Description

Trk Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16725-50, BZ16725-100

Product: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Swiss-Prot: P04629/Q16288/Q16620

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-P, ICC/IF

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200

Background: The family of Trk receptor tyrosine kinases consists of TrkA, TrkB, and TrkC. While the sequence of these family members is highly conserved, they are activated by different neurotrophins: TrkA by NGF, TrkB by BDNF or NT4, and TrkC by NT3. Neurotrophin signaling through these receptors regulates a number of physiological processes, such as cell survival, proliferation, neural development, and axon and dendrite growth and patterning.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 87 kDa; Observed MW: 140 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of TrkA+B+C in Human fetal brain lysates using Trk antibody., Immunohistochemistry analysis of paraffin-embedded mouse brain using TrkA+B+C antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval., Immunofluorescence analysis of Trk in Neuro2a using TrkA+B+C antibody.

Alternative Name: gp140trk; GP145-TrkB; GP145-TrkC; MTC; NTRK1; NTRK2; NTRK3; p140-TrkA; TRKA; TRKB; TrkB tyrosine kinase; TRKC

Immunogen: A synthesized peptide derived from human TrkA+B+C

Conjugate: Unconjugated

Modification: Unmodified