TrkB Polyclonal Antibody - E-AB-93271

TrkB Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-93271-60, E-AB-93271-120, E-AB-93271-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: TrkB

Target Synonym: NTRK2; GP145-TrkB; TRKB; trk-B; TrkB; OBHD

Research Areas: Cancer, Metabolism, Neuroscience

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB, IF

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q16620

Background: This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human TrkB

Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IF 1:50-1:200

Calculated MW: 35kDa/53kDa/59kDa/60kDa/81kDa/91kDa/93kDa

Observed MW: 140KDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only