TRMT12 Polyclonal Antibody - E-AB-19045

TRMT12 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-19045-60, E-AB-19045-120, E-AB-19045-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: TRMT12

Target Synonym: Alpha amino alpha carboxypropyl transferase TYW2; FLJ20772; Homolog of yeast tRNA methyltransferase; Radical S-adenosyl methionine and flavodoxin domain-containing protein 2; TRM 12; TRM12; TRMT 12; TRMT12; tRNA methyltransferase 12; tRNA methyltransferase 12 homolog; tRNA wybutosine-synthesizing protein 2 homolog; tRNA-yW-synthesizing protein 2; TYW2; TYW2

Research Areas: Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Rat

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q53H54

Background: Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TRMT12 is the human homolog of a yeast gene essential for yW synthesis (Noma and Suzuki, 2006).

Concentration: 1.44 mg/mL

Immunogen: Fusion protein of human TRMT12

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only