Troponin T-C Polyclonal Antibody - BT-AP09226

Troponin T-C Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP09226-20, BT-AP09226-50, BT-AP09226-100

Citations, Manuals and MSDS Available upon request.

Background: Troponin T cardiac muscle encoded by TNNT2 is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.

Research Areas: Signal Transduction

Target Protein: TNNT2

Applications: WB, IHC-p, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Troponin T-C Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 35924

UniProt Accession: Human: P45379; Mouse: P50752; Rat: P50753

Synonyms: TNNT2; Troponin T, cardiac muscle; TnTc; Cardiac muscle troponin T; cTnT

GeneID: Human: 7139; Mouse: 21956; Rat: 24837

Research Use Only