TRYB1 Polyclonal Antibody - BT-AP15194

TRYB1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP15194-20, BT-AP15194-50, BT-AP15194-100

Citations, Manuals and MSDS Available upon request.

Background: Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3andapos; UTR and contain tandem repeat sequences at the 5andapos; flank and 3andapos; UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate gene

Research Areas: Epigenetics and nuclear signaling; Developmental biology; Stem cells; Tags and cell markers

Target Protein: TPSAB1

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Tryptase alpha/beta-1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q15661; Mouse: Q02844; Rat: P27435

Synonyms: Tryptase alpha/beta-1;Tryptase-1;EC 3.4.21.59;Tryptase I;Tryptase alpha-1

GeneID: Human: 7177

Research Use Only