TSHB Polyclonal Antibody - BT-AP15210

TSHB Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP15210-20, BT-AP15210-50, BT-AP15210-100

Citations, Manuals and MSDS Available upon request.

Background: The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. The protein encoded by this gene is the beta subunit of thyroid stimulating hormone. Mutations in this gene are associated with congenital central and secondary hypothyroidism and Hashimotoandapos;s thyroiditis. Alternative splicing of this gene results in multiple transcript variants.

Research Areas: Signal transduction; Neuroscience; Metabolism; Cancer

Target Protein: TSHB

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Thyrotropin subunit beta

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P01222; Mouse: P12656; Rat: P04652

Synonyms: Thyrotropin subunit beta;Thyroid-stimulating hormone subunit beta;TSH-B;TSH-beta;Thyrotropin beta chain;Thyrotropin alfa

GeneID: Human: 7252

Research Use Only