TSHR Polyclonal Antibody - BT-AP15211

TSHR Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP15211-20, BT-AP15211-50, BT-AP15211-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene.

Research Areas: Signal transduction; Neuroscience

Target Protein: TSHR

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Thyrotropin receptor

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P16473; Mouse: P47750; Rat: P21463

Synonyms: Thyrotropin receptor;Thyroid-stimulating hormone receptor;TSH-R

GeneID: Human: 7253

Research Use Only