TSLPR Monoclonal Antibody - BT-MCA3174

TSLPR Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3174-50, BT-MCA3174-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the type I cytokine receptor family. The encoded protein is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Rearrangement of this gene with immunoglobulin heavy chain gene (IGH) on chromosome 14, or with P2Y purinoceptor 8 gene (P2RY8) on the same X or Y chromosomes is associated with B-progenitor acute lymphoblastic leukemia (ALL) and Down syndrome ALL. Alternatively spliced transcript variants have been found for this gene.

Research Areas: Others

Target Protein: TSLPR

Applications: IHC, FCM

Clonality: Monoclonal

Clone ID: 1E10D3

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: TSLPR

Immunogen: Purified recombinant fragment of human TSLPR (AA: extra(23-231)) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 42kDa

UniProt Accession: Q9HC73

Synonyms: CRL2, TSLPR, CRLF2Y

GeneID: 64109

Research Use Only