Product Description

TUBB2A (Acetyl-K379) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS64103-50, BS64103-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Tubμlin is a major cytoskeleton component that has five distinct forms, designated a, b, g, d and e tubμlin. a and b tubμlins form heterodimers which mμltimerize to form a microtubμle filament. Mμltiple b Tubμlin isoforms (b1, b2, b3, b4, b5, b6 and b8) have been characterized and are expressed in mammalian tissues. b1 and b4 are present throughout the cytosol, b2 is present in the nuclei and nucleoplasm, and b3 is a neuron-specific cytoskeletal protein. g Tubμlin forms the gammasome, which is required for nucleating microtubμle filaments at the centrosome. Both d Tubμlin and e Tubμlin are associated with the centrosome. d Tubμlin is a homolog of the Chlamydomonas d Tubμlin Uni3 and is found in association with the centrioles, whereas e Tubμlin localizes to the pericentriolar material. e Tubμlin exhibits a cell cycle-specific pattern of localization, first associating with only the older of the centrosomes in a newly duplicated pair, and later associating with both centrosomes.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Tubμlin beta-2A chain, Tubμlin beta class IIa, TUBB2A, Tubμlin beta-2B chain, TUBB2B, Tubμlin beta-3 chain, Tubμlin beta-4 chain, Tubμlin beta-III, TUBB3, Tubμlin beta-4B chain, Tubμlin beta-2 chain, Tubμlin beta-2C chain, TUBB4B, Tubμlin beta chain, Tubμlin beta-5 chain, TUBB, Tubμlin beta-6 chain, Tubμlin beta class V, TUBB6

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Acetylated

Immunogen: Synthetic Acetylated peptide derived from human TUBB2A around the Acetylation site of K379.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: TUBB2A (Acetyl-K379) polyclonal antibody detects endogenous levels of TUBB2A protein only when acetylated at Lys379. This antibody also recognizes TUBB2B/3/4A/4B/6 protein when acetylated at the corresponding residues.

Molecular Weight: ~ 49 kDa

Pathway: Regμlation of Microtubμle Dynamics,

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q13885/Q9BVA1/Q13509/P04350/P68371/P07437/Q9BUF5

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only