TYR Polyclonal Antibody - E-AB-64747

TYR Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-64747-60, E-AB-64747-120, E-AB-64747-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: TYR

Target Synonym: TYR; ATN; CMM8; OCA1; OCA1A; OCAIA; SHEP3

Research Areas: Cancer,Metabolism,Signal Transduction,Tags and Cell Markers

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Rat

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P14679

Background: The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene.

Concentration: 1 mg/mL

Immunogen: Recombinant fusion protein of human TYR

Buffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 42kDa/60kDa

Observed MW: 80kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only