UB2E3 Polyclonal Antibody - BT-AP15281

UB2E3 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP15281-20, BT-AP15281-50, BT-AP15281-100

Citations, Manuals and MSDS Available upon request.

Background: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse and rat counterparts, which indicates that this enzyme is highly conserved in eukaryotes. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.

Research Areas: Epigenetics and nuclear signaling; Cell biology

Target Protein: UBE2E3

Applications: WB, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Ubiquitin-conjugating enzyme E2 E3

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q969T4; Mouse: P52483

Synonyms: Ubiquitin-conjugating enzyme E2 E3;EC 6.3.2.19;UbcH9;Ubiquitin carrier protein E3;Ubiquitin-conjugating enzyme E2-23 kDa;Ubiquitin-protein ligase E3

GeneID: Human: 10477

Research Use Only