Product Description

UBE2Z Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES10446-50, ES10446-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes an enzyme which ubiquitinates proteins which participate in signaling pathways and apoptosis. [provided by RefSeq, Feb 2012],

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from part region of human protein

Isotype: IgG

Target: UBE2Z

Specificity: UBE2Z Polyclonal Antibody detects endogenous levels of protein.

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Expression: Widely expressed, Highly in placenta, pancreas, spleen and testis,

Observed Band (KD): 38kD

Fields: Ubiquitin mediated proteolysis

Function: Catalytic Activity: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine
Function: Catalyzes the covalent attachment of ubiquitin to other proteins (By similarity). Specific substrate for UBE1L2, not charged with ubiquitin by UBE1. May be involved in apoptosis regulation
Pathway: Protein modification, protein ubiquitination
Similarity: Belongs to the ubiquitin-conjugating enzyme family
Tissue Specificity: Widely expressed. Highly in placenta, pancreas, spleen and testis

Subcellular Location: Cytoplasm Nucleus

Storage and Stability: -20°C/1 year

Gene Name: UBE2Z HOYS7

Protein Name: Ubiquitin-conjugating enzyme E2 Z (EC 6.3.2.19) (Uba6-specific E2 conjugating enzyme 1) (Use1) (Ubiquitin carrier protein Z) (Ubiquitin-protein ligase Z)

Mouse SwissProt Number: Q3UE37

Rat SwissProt Number: Q3B7D1

Research Use Only