Product Description

UBE3C Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA35815-50, RA35815-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: function:E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo., miscellaneous:A cysteine residue is required for ubiquitin-thioester formation., pathway:Protein modification; protein ubiquitination., similarity:Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain., similarity:Contains 1 IQ domain., subunit:Interacts with 26S proteasomes. Binds CAND2., tissue specificity:Highly expressed in skeletal muscle. Detected at much lower levels in kidney and pancreas.,

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, ELISA

Alternate Names: UBE3C, KIAA0010, KIAA10, Ubiquitin-protein ligase E3C, HectH2

Clonality: Polyclonal

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Molecular Weight: 125

Protein Molecular Weight (kDa): 125

Storage: -20°C/1 year

Human Gene ID: 148581

Human SwissProt Number: Q15386

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only