Ubiquitin mouse Monoclonal Antibody (5F1) - BT-MCA0078

Ubiquitin mouse Monoclonal Antibody (5F1)

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-MCA0078-20, BT-MCA0078-50, BT-MCA0078-100

Citations, Manuals and MSDS Available upon request.

Background: UBB (ubiquitin B) encodes ubiquitin, one of the most conserved proteins known. Ubiquitin has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. UBB consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. An aberrant form of this protein has been detected in patients with Alzheimer's disease and Down syndrome. Pseudogenes of UBB are located on chromosomes 1, 2, 13, and 17. Alternative splicing results in multiple transcript variants.

Research Areas: Cell biology; Epigenetics and nuclear signaling; Neuroscience

Target Protein: Ubiquitin

Applications: WB, IF, ICC, IHC-p

Reactivity: Human,Rat,Mouse

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Ubiquitin

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: PAN

GeneID: Human: 7314

Research Use Only