UBQLN1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A15439-20, A15439-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Mouse, Rat
Protein Weight: 63kDa
Observed Molecular Weight: 70kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 29979
SWISS: Q9UMX0
Alternate Names: DA41; DSK2; UBQN; XDRP1; PLIC-1; UBQLN1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:200 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cell Biology Developmental Biology, Ubiquitin.
NCBI Alias: UBQLN1
Research Use Only