Product Description

UCN3 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-17833-60, E-AB-17833-120, E-AB-17833-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: UCN3

Target Synonym: MGC119002; OTTHUMP00000018999 ; Prepro urocortin 3; SCP; SPC; Stresscopin ; Ucn III ; UCN3 ; UCN3 urocortin 3 stresscopin; UCNIII; Urocortin 3; Urocortin 3 stresscopin; Urocortin III

Research Areas: Cancer, Cardiovascular, Metabolism, Neuroscience, Signal transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q969E3

Background: This gene encodes a member of the sauvagine/corticotropin-releasing factor/urotensin I family of proteins. The encoded preproprotein is proteolytically processed to generate the mature peptide hormone, which is secreted by pancreatic beta and alpha cells. This hormone is an endogenous ligand for corticotropin-releasing factor receptor 2 and may regulate insulin secretion in response to plasma glucose levels. Patients with type 2 diabetes exhibit reduced levels of the encoded protein in beta cells. In the brain, the encoded protein may be responsible for the effects of stress on appetite.

Concentration: 1.4 mg/mL

Immunogen: Synthetic peptide of human UCN3

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only