Product Description

UCP1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS70689-50, BS70689-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Uncoupling protein 1 (UCP1) is a mitochondrial inner membrane transport protein that is primarily expressed in brown adipose tissue (BAT). UCP1 dissipates the pH gradient resμlting from oxidative phosphorylation, which uncouples ATP synthesis from oxidative phosphorylation and leads to the release of heat energy. As a resμlt, UCP1 plays an important role in thermogenesis. Research studies indicate that subcutaneous white adipose depots in mice contain beige adipocytes that express low levels of UCP1 protein. Additional studies show possible differences in thermogenesis in individuals carrying specific polymorphisms in the corresponding UCP1 gene. Related studies link UCP1 to the possible development of obesity and type 2 diabetes.

Category: Primary Antibody

Reactivity: Mouse, Rat

Host: Rabbit

Applications: WB, IHC, IF

Alternate Names: UCP1, SLC25A7, UCP

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human UCP1 (NP_068605.1).

Dilution: WB: 1:500~1:2000
IHC: 1:50~1:200
IF: 1:50~1:100

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: UCP1 polyclonal antibody detects endogenous levels of UCP1 protein.

Molecular Weight: ~ 30 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P25874

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only