UCP3 Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA35868-50, RA35868-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: uncoupling protein 3 (UCP3) Homo sapiens Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. The different UCPs have tissue-specific expression; this gene is primarily expressed in skeletal muscle. This gene's protein product is postulated to protect mitochondria against lipid-induced oxidative stress. Expression levels of this gene increase when fatty acid supplies to mitochondria exceed their oxidation capacity and the protein enables the export of fatty acids from mitochondria. Reactivity: Human, Mouse, Rat Host: Rabbit Applications: WB, ELISA Alternate Names: UCP3, SLC25A9, Mitochondrial uncoupling protein 3, UCP 3, Solute carrier family 25 member 9 Clonality: Polyclonal Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. Molecular Weight: 33 Protein Molecular Weight (kDa): 33 Storage: -20°C/1 year Human Gene ID: 7352 Human SwissProt Number: P55916 Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Research Use Only