UDG Polyclonal Antibody - BT-AP09405

UDG Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP09405-20, BT-AP09405-50, BT-AP09405-100

Citations, Manuals and MSDS Available upon request.

Background: UNG encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID: 10309), which has been confused with this gene, in the literature and some databases.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: UNG

Applications: WB, IHC-p, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: UDG Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 34645

UniProt Accession: Human: P13051; Mouse: P97931

Synonyms: UNG; DGU; UNG1; UNG15; Uracil-DNA glycosylase; UDG

GeneID: Human: 7374; Mouse: 22256

Research Use Only