UFD2 Polyclonal Antibody - BT-AP09409

UFD2 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP09409-20, BT-AP09409-50, BT-AP09409-100

Citations, Manuals and MSDS Available upon request.

Background: The ubiquitination factor E4B with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE4B encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: UBE4B

Applications: IHC-p, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: UFD2 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 146185

UniProt Accession: Human: O95155; Mouse: Q9ES00

Synonyms: UBE4B; HDNB1; KIAA0684; UFD2; Ubiquitin conjugation factor E4 B; Homozygously deleted in neuroblastoma 1; Ubiquitin fusion degradation protein 2

GeneID: Human: 10277; Mouse: 63958

Research Use Only