UGT1A10 Polyclonal Antibody - E-AB-91570

UGT1A10 Polyclonal Antibody Sizes: 60μL, 120μL, 200μL Catalogue Numbers: E-AB-91570-60, E-AB-91570-120, E-AB-91570-200 Citations, Manuals and MSDS Available upon request. Abbreviation: UGT1A10 Target Synonym: UGT1A10; UDPGT; UGT-1J; UGT1-10; UGT1.10; UGT1J Research Areas: Metabolism, Signal Transduction Conjugation: Unconjugated Host: Rabbit Species Reactivity: Human Application: WB Isotype: IgG Clonality: Polyclonal UNIProt ID: Q9HAW8 Background: This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene has glucuronidase activity on mycophenolic acid, coumarins, and quinolines. Concentration: 1mg/mL Immunogen: A synthetic peptide of human UGT1A10 Buffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3. Purification Method: Affinity purification Dilution: WB 1:500-1:2000 Calculated MW: 49kDa/59kDa Observed MW: 60kDa Storage: -20°C/One year. Avoid freeze / thaw cycles. Shipping: Ice bag Research Use Only