Product Description

UNC5D Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA35913-50, RA35913-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: function:Receptor for netrin. May be involved in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand., PTM:Phosphorylated on cytoplasmic tyrosine residues., PTM:Proteolytically cleaved by caspases during apoptosis. The cleavage does not take place when the receptor is associated with netrin ligand. Its cleavage by caspases is required to induce apoptosis., similarity:Belongs to the unc-5 family., similarity:Contains 1 death domain., similarity:Contains 1 Ig-like (immunoglobulin-like) domain., similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain., similarity:Contains 1 ZU5 domain., similarity:Contains 2 TSP type-1 domains., subunit:Interacts with the cytoplasmic part of DCC.,

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 104

Protein Molecular Weight (kDa): 104

Storage: -20°C/1 year

Human Gene ID: 137970

Human SwissProt Number: Q6UXZ4

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only