Product Description

VASN Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES10988-50, ES10988-100

Lead times: approximately 7-10 business days, if manufacturer has product in stock

Manufacturer/Ship Location: China

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from part region of human protein

Isotype: IgG

Target: VASN,

Specificity: VASN Polyclonal Antibody detects endogenous levels of protein.

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formulation: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Expression: Expressed at highest levels in aorta, at intermediate levels in kidney and placenta and at lowest levels in brain, heart, liver, lung and skeletal muscle. Within the aorta, the strongest expression is found in the tunica media of the proximal ascending aorta, the descending thoracic aorta, the abdominal aorta and the coronary arteries. Within the kidney, expression is found in the interstitial cells.

Observed Band (KD): 74kD

Function: May act as an inhibitor of TGF-beta signaling. PTM: N-glycosylated. Similarity: Contains 1 EGF-like domain. Similarity: Contains 1 fibronectin type-III domain. Similarity: Contains 11 LRR (leucine-rich) repeats. Subunit: Interacts with TGFB1, TGFB2 and TGFB3. Tissue Specificity: Expressed at highest levels in aorta, at intermediate levels in kidney and placenta and at lowest levels in brain, heart, liver, lung and skeletal muscle. Within the aorta, the strongest expression is found in the tunica media of the proximal ascending aorta, the descending thoracic aorta, the abdominal aorta and the coronary arteries. Within the kidney, expression is found in the interstitial cells.

Subcellular Location: Membrane, Single-pass type I membrane protein Secreted

Storage and Stability: -20°C/1 year

Gene Name: VASN, SLITL2, UNQ314/PRO357/PRO1282

Protein Name: Vasorin, Protein slit-like 2

Human Gene ID: 114990

Human SwissProt Number: Q6EMK4

Mouse SwissProt Number: Q9CZT5

Research Use Only