VASP Monoclonal Antibody - BT-MCA2964

VASP Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2964-50, BT-MCA2964-100

Citations, Manuals and MSDS Available upon request.

Background: Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. [provided by RefSeq, Jul 2008]

Research Areas: Signal Transduction

Target Protein: VASP

Applications: WB, IHC, ICC, FCM

Clonality: Monoclonal

Clone ID: 6B10A1

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: VASP

Immunogen: Purified recombinant fragment of human VASP (AA: 1-380) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 39.8kDa

UniProt Accession: P50552

GeneID: 7408

Research Use Only