VDAC3 Polyclonal Antibody - BT-AP15446

VDAC3 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP15446-20, BT-AP15446-50, BT-AP15446-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a voltage-dependent anion channel (VDAC), and belongs to the mitochondrial porin family. VDACs are small, integral membrane proteins that traverse the outer mitochondrial membrane and conduct ATP and other small metabolites. They are known to bind several kinases of intermediary metabolism, thought to be involved in translocation of adenine nucleotides, and are hypothesized to form part of the mitochondrial permeability transition pore, which results in the release of cytochrome c at the onset of apoptotic cell death. Alternatively transcript variants encoding different isoforms have been described for this gene.

Research Areas: Signal transduction; Cancer; Cell biology; Metabolism

Target Protein: VDAC3

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Voltage-dependent anion-selective channel protein 3

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q9Y277; Mouse: Q60931; Rat: Q9R1Z0

Synonyms: Voltage-dependent anion-selective channel protein 3;VDAC-3;hVDAC3;Outer mitochondrial membrane protein porin 3

GeneID: Human: 7419

Research Use Only