Visfatin Monoclonal Antibody - BT-MCA3808

Visfatin Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3808-50, BT-MCA3808-100

Citations, Manuals and MSDS Available upon request.

Background: Visfatin, a newly identified adipocytokine ,which is predominantly secreted from visceral adipose tissue both in humans and mice . Visfatin corresponds to a protein identified previously as pre-B cell colony-enhancing factor (PBEF). Visfatin exerted insulin-mimetic effects in cultured cells, various insulin-sensitive tissues such as liver, muscle, and fat ,and lowered plasma glucose levels in mice. Mice heterozygous for a targeted mutation in the visfatin gene had modestly higher levels of plasma glucose relative to wild-type littermates. visfatin binds to and activates the insulin receptor. Which may lead to new insights into glucose homeostasis and/or new therapies for metabolic disorders such as diabetes.

Research Areas: Others

Target Protein: Visfatin

Reactivity: Human

Clonality: Monoclonal

Clone ID: 4E11C9

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: Visfatin

Immunogen: Purified recombinant fragment of Visfatin expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

UniProt Accession: P43490

Synonyms: PBEF, MGC117256

GeneID: 10135

Research Use Only