WISP-3 Polyclonal Antibody - RA36187

WISP-3 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA36187-50, RA36187-100

Citations, Manuals and MSDS Available upon request.

Background: WNT1 inducible signaling pathway protein 3 (WISP3) Homo sapiens This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. This gene is overexpressed in colon tumors. It may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Mutations of this gene are associated with progressive pseudorheumatoid dysplasia, an autosomal recessive skeletal disorder, indicating that the gene is essential for normal postnatal skeletal growth and cartilage homeostasis. Multiple

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:500-2000, ELISA 1:10000-20000

Alternative Names: WNT1-inducible-signaling pathway protein 3 (WISP-3) (CCN family member 6)

Applications: WB; ELISA

Species Cross-Reactivity: Human; Rat; Mouse

GeneID (Human): 8838

Protein MW (KDa): 55

SWISS: O95389

Source: Rabbit

Research Use Only