Product Description

WNK4 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-19365-60, E-AB-19365-120, E-AB-19365-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: WNK4

Target Synonym: PHA 2B; PHA2B; PRKWNK 4; PRKWNK4; Protein kinase lysine deficient 4; Protein kinase lysine-deficient 4; Protein kinase with no lysine 4; Serine/threonine protein kinase WNK4; Serine/threonine-protein kinase WNK4; WNK lysine deficient protein kinase 4; Wnk4; WNK4

Research Areas: Signal transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q96J92

Background: This gene encodes a member of the WNK family of serine-threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K(+) secretion. The kinase regulates the activities of several types of ion channels, cotransporters, and exchangers involved in electrolyte flux in epithelial cells. Mutations in this gene result in pseudohypoaldosteronism type IIB.

Concentration: 1.32 mg/mL

Immunogen: Synthetic peptide of human WNK4

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:40-1:200, ELISA 1:5000-1:10000

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only