X11β Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA36217-50, RA36217-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: amyloid beta precursor protein binding family A member 2 (APBA2) Homo sapiens The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], Reactivity: Human, Mouse, Rat Host: Rabbit Applications: IHC-p, IF (paraffin section), WB, ELISA Alternate Names: APBA2, MINT2, X11L, Amyloid beta A4 precursor protein-binding family A member 2, Adapter protein X11beta, Neuron-specific X11L protein, Neuronal Munc18-1-interacting protein 2, Mint-2 Clonality: Polyclonal Dilution: WB 1:500-2000 Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. Molecular Weight: 83 Protein Molecular Weight (kDa): 83 Storage: -20°C/1 year Human Gene ID: 321 Human SwissProt Number: Q99767 Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Research Use Only