X11β Polyclonal Antibody - RA36217

X11β Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA36217-50, RA36217-100 Citations, Manuals and MSDS Available upon request. Background: amyloid beta precursor protein binding family A member 2 (APBA2) Homo sapiens The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP) . It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions: -20°C/1 year Recommended dilutions: WB 1:500-2000 Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. Alternative Names: APBA2; MINT2; X11L; Amyloid beta A4 precursor protein-binding family A member 2; Adapter protein X11beta; Neuron-specific X11L protein; Neuronal Munc18-1-interacting protein 2; Mint-2 Applications: IHC-p; IF (paraffin section) ; WB; ELISA Species Cross-Reactivity: Human; Mouse; Rat GeneID (Human): 321 Protein MW (KDa): 83 SWISS: Q99767 Source: Rabbit Research Use Only