XDH Polyclonal Antibody - E-AB-65997

XDH Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-65997-60, E-AB-65997-120, E-AB-65997-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: XDH

Target Synonym: XDH; XAN1; XO; XOR

Research Areas: Cancer, Metabolism, Signal transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Mouse

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P47989

Background: Xanthine dehydrogenase belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Xanthine dehydrogenase can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human XDH (NP_000370.2).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 146kDa

Observed MW: 146kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only