XPC Monoclonal Antibody - BT-MCA3924

XPC Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3924-50, BT-MCA3924-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a key component of the XPC complex, which plays an important role in the early steps of global genome nucleotide excision repair (NER). The encoded protein is important for damage sensing and DNA binding, and shows a preference for single-stranded DNA. Mutations in this gene or some other NER components can result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.

Research Areas: Epigenetics and nuclear signaling

Target Protein: XPC

Applications: WB, FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 5F4B11

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: XPC

Immunogen: Purified recombinant fragment of human XPC (AA: 32-133) expressed in mammalian.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 106kDa

UniProt Accession: Q01831

Synonyms: XP3, RAD4, XPCC, p125

GeneID: 7508

Research Use Only