XRCC1 Monoclonal Antibody - BT-MCA4201

XRCC1 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4201-50, BT-MCA4201-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: XRCC1

Applications: WB, IHC, FCM

Clonality: Monoclonal

Clone ID: 4D10D3

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: XRCC1

Immunogen: Purified recombinant fragment of human XRCC1 (AA: 1-150) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 69.5kDa

UniProt Accession: P18887

Synonyms: RCC, SCAR26

GeneID: 7515

Research Use Only