XRCC1 Polyclonal Antibody - BT-AP09623

XRCC1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP09623-20, BT-AP09623-50, BT-AP09623-100

Citations, Manuals and MSDS Available upon request.

Background: DNA repair protein XRCC1 encoded by XRCC1 is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: XRCC1

Applications: WB, IHC-p, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: XRCC1 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 69526

UniProt Accession: Human: P18887; Mouse: Q60596; Rat: Q9ESZ0

Synonyms: XRCC1; DNA repair protein XRCC1; X-ray repair cross-complementing protein 1

GeneID: Human: 7515; Mouse: 22594; Rat: 84495

Research Use Only