XRCC2 (F240) Polyclonal Antibody-BS1494

XRCC2 (F240) Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS1494-50, BS1494-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: O43543

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: IHC

All Applications: IHC: 1:50~1:200

Background: The x-ray repair cross-complementing (XRCC) proteins are responsible for efficiently repairing and maintaining genetic stability following DNA base damage. These genes share sequence similarity with the yeast DNA repair protein Rad5. XRCC1 is a protein that facilitates the DNA base excision repair pathway by interacting with DNA ligase III and DNA polymerase to repair DNA single-strand breaks. XRCC2 and XRCC3 are both involved in maintaining chromosome stability during cell division. XRCC2 is required for efficient repair of DNA double-strand breaks by homologous recombination between sister chromatids, and XRCC3 interacts directly with Rad51 to cooperate with Rad51 during recombinational repair.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemistry (IHC) analyzes of XRCC2 (F240) pAb in paraffin-embedded human lung carcinoma tissue.

Bioworld Molecular Weight: ~ 32 kDa

Specificity: XRCC2 (F240) polyclonal antibody detects endogenous levels of XRCC2 protein.

Alternative Name: DNA repair protein XRCC2; X-ray repair cross-complementing protein 2; XRCC2

Immunogen: Synthetic peptide, corresponding to amino acids 211-260 of Human XRCC2.

Conjugate: Unconjugated

Modification: Unmodified