XRCC5 Monoclonal Antibody - BT-MCA2525

XRCC5 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2525-50, BT-MCA2525-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: XRCC5

Applications: WB, IHC, ICC, FCM

Reactivity: Human, Mouse

Clonality: Monoclonal

Clone ID: 5C5

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: XRCC5

Immunogen: Purified recombinant fragment of human XRCC5 expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 86kDa

UniProt Accession: P13010

Synonyms: KU80, KUB2, Ku86, NFIV, KARP1, KARP-1, FLJ39089

GeneID: 7520

Research Use Only