Product Description

Z280B Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES10322-50, ES10322-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The protein encoded by this gene is a transcription factor that upregulates expression of MDM2, which negatively regulates p53 expression. This gene is highly expressed in prostate cancer cells, which leads to a reduction in p53 levels and an increase in growth of the cancer cells. Several transcript variants have been found for this gene, but only one of them is protein-coding. [provided by RefSeq, Jan 2015],

Reactivity: Human, Rat, Mouse,

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from part region of human protein

Isotype: IgG

Target: Z280B

Specificity: Z280B Polyclonal Antibody detects endogenous levels of protein.

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Expression: Testis, Uterus,

Observed Band (KD): 59kD

Function: Function: May function as a transcription factor
PTM: Phosphorylated upon DNA damage, probably by ATM or ATR
Similarity: Contains 4 C2H2-type zinc fingers

Subcellular Location: Nucleus

Storage and Stability: -20°C/1 year

Gene Name: ZNF280B SUHW2 ZNF279 ZNF632

Protein Name: Zinc finger protein 280B (5'OY11.1) (Suppressor of hairy wing homolog 2) (Zinc finger protein 279) (Zinc finger protein 632)

Research Use Only